A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice.
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چکیده
منابع مشابه
A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice
Interleukin 1 (IL-1) is an endogenously produced cytokine that mediates a variety of physiological effects that may be beneficial or deleterious to the host. C57Bl/6 mice treated intravenously with a recently characterized human recombinant receptor antagonist protein to IL-1 (IL-1ra) had improved survival when treated after a lethal Escherichia coli endotoxin (lipopolysaccharide [LPS]) challen...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1991
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.173.4.1029